Method development
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Feasibility assessment, method establishment and development
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Experience with a variety of species and matrices
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Wide selection of analytical methodologies available
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Immunogen synthesis
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Antibody characterisation and production
Method Validation
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GLP/GCP Validation in accordance with current industry recommendations
Sample Analysis
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PK Bioanalysis
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Immunogenicity testing
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Rapid sample turnaround
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Automated sample handling
Analytical methods & instrumentation
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ELISA, EIA, DELFIA, IRMA,and RIA
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Multiplex systems under evaluation
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Olympusä
, Immuliteä
and Axsymä
analyser systems for clinical biomarkers
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Range of detection techniques - colorimetric, radiometric, fluorescence,
chemiluminescence and time resolved fluorescence
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MALDI-MS, LC-MS/MS, GC-MS/MS
including HFL’s BioMSä service
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Electrophoresis and affinity chromatography
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Mitsubishi robotic system for 96/384 well plate technology incorporating
Multiprobe IIä
and precision pipetting using Evolution P3
systems
High throughput automated protein quantification using Gyrolabä platform
Using the Gyrolab
ä platform
, HFL are able to offer:
-
Enhanced performance and productivity
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Lower serum dilutions increase assay sensitivity
-
Automation minimises performance failures and improves reproducibility
-
Reduced sample size requirements leading to reduced reagent consumption
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