With over 40 years experience as a forensic laboratory, HFL's core competence is drug analysis. Our experienced staff and up-to-date technology allow HFL to provide high quality bioanalytical services to support all stages of drug development:

Method development

• Feasibility assessment, method establishment and development
• Experience with a variety of species and matrices
• Wide library of reference standards, including many controlled drugs
• Obtaining custom synthesised stable-isotope labelled internal standards

Method Validation

• GLP/GCP Validation in accordance with current industry recommendations
• Library of non-proprietary validated methods

Sample Analysis

• Rapid sample turnaround
• Automated sample handling

 
Analytical methods & instrumentation

• APCI, ESI and EI/CI systems
• SCIEX API-3000ä , API-4000ä  and 5000ä  LC-MS/MS
• Waters UPLCä 
• Waters Quattro Premierä  LC-MS/MS
• Varian 1200Lä  GC-MS/MS
• 96-well plate technology using MulitPROBEä  robotic systems
• PK/TK analysis using Kineticaä

Metabonomic/metabolomics 

• Highest quality data for 'omics' investigations
• GC-MS and LC-MS methodologies
• Range of statistical data analysis techniques